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Wednesday 26 June 2013

More on Grahams post last night re. weight loss and diabetic outcomes.

Check out Graham’s post last night and you would get the impression weight loss was a waste of time in diabetics regarding heart attacks and stroke, pretty depressing read for sure. But and it is a very big but ! all the participants had extremely poor HbA1c numbers. Are you getting the big picture ? Also the intensive control group were on a heavy duty medication regime, including drugs now banned for killing people. Check out what I wrote some months ago when this Look Ahead Trial was abandoned, for being a waste of time and a huge amount of money. The problem with far too many medics, is the fact that HbA1c makes all the difference in the world for a diabetic and staying complication free, the medics have yet to learn that fact.

Eddie

$220 million well spent ! Proves NHS,DUK,ADA dietary information for type two diabetics useless !

The most damning piece of information regarding diet for type two diabetics, I have ever read in four years of studying type two diabetes, was the complete failure of the Look Ahead Trial to improve CVD outcomes for type two diabetics. By  using a modest reduction in weight and calorie reduction, the trial participants were on a 55% carb diet, the trial was doomed to fail from day one ! I am wading through a mass of information, but one thing stands out a mile, the pitiful reduction in HbA1c (see chart below). The participants had a top HbA1c of eleven at the start of the trial, higher numbers excluded from taking part. After 11 years of a 13 year trial it was deemed ‘futile’ to continue. No benefits in outcomes regarding CVD among the participants was found. Average HbA1c reduction 0.5% and the boffins expected an improvement in CVD, what planet are these people on !

With the correct diet it would be normal to see massive reductions in HbA1c and vastly improved blood glucose control. Huge reductions in obesity, far better lipid counts and huge reductions in medication used. This has been proved countless times by lowcarbing diabetics, and they didn’t need 11 years and $220 million to find out a way to improve CVD. The good news we see on blogs and forums all over the world, counts for nothing with outfits like the NHS,DUK and the ADA, they call the good news reported ‘anecdotal’ they much prefer to accept the information received from big pharma and junk food companies. The fact that many of these outfits have been fined $billions for lying, bribery and corruption and falsifying drug trial evidence matters not a jot. Why, because the people we should be able to trust have sold out, and put money before peoples health and wellbeing. We need far more people like Bernstein, Wortman, Taubes, Kendrick, Briffa et al. They have the courage to stick their heads above the parapet, and refuse to be lackeys and yes men to stupidity and greed.


Some HbA1c facts
For every percentage point drop in A1C blood test results (from 8.0 percent to 7.0 percent, for example), the risk of diabetic eye, nerve, and kidney disease is reduced by 40 percent. Lowering blood sugar reduces these microvascular complications in both type 1 and type 2 diabetes. Intensive blood sugar control in people with type 1 diabetes (average A1C of 7.4%) reduces the risk of any CVD event by 42 percent and the risk of heart attack, stroke, or death from CVD by 57 percent. 

Source: DCCT/EDIC, reported in December 22, 2005, issue of the New England Journal of Medicine.


Hi folks, please spare a thought for the Medics, evidently they are 'perplexed' as to the best way to treat hyperglycaemia in type two diabetics. The truth is they are perplexed how to treat most conditions in type two diabetics. The $200 million plus Look Ahead Trial proved one thing without a shadow of a doubt. A reduced calorie diet with modest exercise done nothing for type two diabetic outcomes regarding CVD. It also proved the diet of death pushed by the NHS, DUK and ADA i.e. 55% carbs does no diabetic any favours. The other question I’m asking myself is what meds were involved ? Actos, Avandia etc. etc. One thing is for sure, type two diabetics on a 55% carb diet must have made med taking a full time job.

Well those good guys at the ADA wanted to ease the burden on these 'perplexed' Medics.

"As a consequence, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) convened a joint task force to examine the evidence and develop recommendations for antihyperglycemic therapy in nonpregnant adults with type 2 diabetes"

The Task Force, anyone smelling a rat ?


R.M. Bergenstal: membership of scientific advisory boards and consultation for or clinical research support with Abbott Diabetes Care, Amylin, Bayer, Becton Dickinson, Boehringer Ingelheim, Calibra, DexCom, Eli Lilly, Halozyme, Helmsley Trust, Hygieia, Johnson & Johnson, Medtronic, NIH, Novo Nordisk, Roche, Sanofi, and Takeda (all under contracts with his employer). Inherited stock in Merck (held by family)
J.B. Buse: research and consulting with Amylin Pharmaceuticals, Inc.; AstraZeneca; Biodel Inc.; Boehringer Ingelheim; Bristol-Myers Squibb Company; Diartis Pharmaceuticals, Inc.; Eli Lilly and Company; F. Hoffmann-La Roche Ltd; Halozyme Therapeutics; Johnson & Johnson; Medtronic MiniMed; Merck & Co., Inc.; Novo Nordisk; Pfizer Inc.; Sanofi; and TransPharma Medical Ltd (all under contracts with his employer)
M. Diamant: member of advisory boards of Abbott Diabetes Care, Eli Lilly, Merck Sharp & Dohme (MSD), Novo Nordisk, Poxel Pharma. Consultancy for: Astra-BMS, Sanofi. Speaker engagements: Eli Lilly, MSD, Novo Nordisk. Through Dr. Diamant, the VU University receives research grants from Amylin/Eli Lilly, MSE, Novo Nordisk, Sanofi (all under contracts with the Institutional Research Foundation)
E. Ferrannini: membership on scientific advisory boards or speaking engagements for: Merck Sharp & Dohme, Boehringer Ingelheim, GlaxoSmithKline, BMS/AstraZeneca, Eli Lilly & Co., Novartis, Sanofi. Research grant support from: Eli Lilly & Co. and Boehringer Ingelheim
S.E. Inzucchi: advisor/consultant to: Merck, Takeda, Boehringer Ingelheim. Research funding or supplies to Yale University: Eli Lilly, Takeda. Participation in medical educational projects, for which unrestricted funding from Amylin, Eli Lilly, Boehringer Ingelheim, Merck, Novo Nordisk, and Takeda was received by Yale University
D.R. Matthews: has received advisory board consulting fees or honoraria from Novo Nordisk, GlaxoSmithKline, Novartis, Eli Lilly, Johnson & Johnson, and Servier. He has research support from Johnson & Johnson and Merck Sharp & Dohme. He has lectured for Novo Nordisk, Servier, and Novartis
M. Nauck: has received research grants (to his institution) from AstraZeneca, Boehringer Ingelheim, Eli Lilly & Co., Merck Sharp & Dohme, Novartis Pharma, GlaxoSmithKline, Novo Nordisk, Roche, and Tolerx. He has received consulting and travel fees or honoraria for speaking from AstraZeneca, Berlin-Chemie, Boehringer Ingelheim, Bristol-Myers Squibb, Diartis, Eli Lilly & Co., F. Hoffmann-La Roche Ltd, Intarcia Therapeutics, Merck Sharp & Dohme, Novo Nordisk, Sanofi-Aventis Pharma, and Versartis
A.L. Peters: has received lecturing fees and/or fees for ad hoc consulting from Amylin, Lilly, Novo Nordisk, Sanofi, Takeda, Boehringer Ingelheim
A. Tsapas: has received travel grant, educational grant, research grant and lecture fees from Merck Serono, Novo Nordisk, and Novartis, respectively.

Eddie


8 comments:

Anonymous said...

Highly recommended read
Jeff

Anonymous said...

Do you lampoon others? YES

Do you give great articles? YES

Definitely recommended read as Jeff says.
Kate

Lowcarb team member said...

Thanks folks, we do what is says on the tin !

Regards Eddie

Lisa said...

That just makes my blood boil!! My 13 year old son has had type 1 for 7 months. I was told not to put him on a low carb diet. Because I have a useful brain, I did my own research and put our whole family on a low carb, no processed food, no grain, no industrial oil diet. His average BG is 6, and his HbA1c is 5.5%. He uses minimal insulin. He exercises regularly. He spends time in the sun to synthesize vitamin D. It's not difficult at all to control his diabetes. I love your blog, so keep up the good posts. We need to educate every diabetic about the relationship between diet and BGs.

Anonymous said...

Good post!

I had my yearly check up with the consultant and again I was quite amazed at how he only hears what he wants to hear. I tell him I low carb, he mutters a bit and then says well as long as you are not eating fat and not eating too much protein that's fine. Perhaps there is another food group that he's referring to which has not been disclosed to me which he assumes I'm eating?

Anyway, in general I like the guy and he said 2 interesting things to me; firstly the DCCT that Eddie quotes is the gold standard diabetic study that the NHS refers to; so if we are to argue with doctors we have to do on the grounds of the evidence in that study (much of which very strongly supports a reduced HbA1c). The second thing he said was that in the 1950's the advice was to low carb but that was stopped when large numbers of diabetics died of CVD.

Has anyone heard of that? Is there any evidence of that? I think this goes to the heart of the NHS Fear of Fat. It would be wonderful if we could directly address that; because if we could the whole edifice would come tumbling down (possibly...)

Finally he said the most important thing is controlling your blood pressure because that damages your blood vessels, also you must reduce your cholesterol because that builds up where your blood vessels are damaged and uncontrolled blood sugars will cause you to put on weight and increase your blood pressure. I just smiled ruefully and took my blood results.

That suggestion; blood pressure, cholesterol, blood sugars and in that order is completely arse over tit (if you'll excuse me). As we all know it's the blood sugars first and foremost; get them right and everything else will follow. But that view is what we are up against. Evidence based medicine eh?

Best

Dillinger

paul1976 said...

"That suggestion; blood pressure, cholesterol, blood sugars and in that order is completely arse over tit (if you'll excuse me). As we all know it's the blood sugars first and foremost; get them right and everything else will follow"

That's certainly been my experience too,even my eGFR and liver function tests have improved as well as cholesteral and BP..BUT somehow HCP's STILL believe I am setting myself up for future nasties..What will it take eh?

Best regards

Paul

Lowcarb team member said...

Hi Lisa

Do you realize how special your son is ? OK sounds a pretty stupid comment. But in the UK 93% of type one diabetics never get to 6.5% Hba1c. He is very lucky to have you. Thank you for your kind words.

Good health and luck to you and yours.

Eddie

Lowcarb team member said...

To Paul and Dillinger spotonski !

A safe HbA1c is paramount in the control of complications, but you guys know that already. What a tragedy far too many medics have not got a clue regarding the long term benefits of good BG control, or how to get it. The good news is people all over the world are trying lowcarb and seeing an amazing turn around in controlling their diabetes.

Thanks for your support Guys, it keeps us going.

Eddie